Which statement correctly describes the idea of biocompatibility for biomaterials?

Answer: B. The ability to perform the required function in a specific application with an appropriate host response

Biocompatibility is not an intrinsic property of a material; it is defined as "the ability of a material to perform with an appropriate host response in a specific application". Alumina and zirconia, which do not react with bone, suit the femoral heads of artificial hip joints, but materials that fill bone defects are actually expected to react, by bonding to bone or by being resorbed and replaced by bone. Because the desirable response differs by application in this way, not reacting at all is not a requirement. And even a material with no toxic elements is not compatible with an application if it is so stiff that it causes stress shielding, if its wear debris causes inflammation, or if it forms thrombi in contact with blood. The shape, surface condition and location of use are evaluated as well.