What is Hydroxyapatite?

A calcium phosphate with the formula Ca₁₀(PO₄)₆(OH)₂. Close to the mineral component of bones and teeth, it is used as a bioactive ceramic that bonds directly to bone. Its Ca/P ratio is 1.67.

Japanese name: ハイドロキシアパタイト

Hydroxyapatite appears in 3 practice questions across 1 topic, including Biomaterials.

Field: Biomaterials

Try it: questions about Hydroxyapatite

What is the Ca/P molar ratio of hydroxyapatite, Ca₁₀(PO₄)₆(OH)₂?

  1. A1.50
  2. B1.33
  3. C1.67
Show answer and explanation

Answer: C. 1.67

The formula contains 10 Ca and 6 P (from the 6 PO₄ groups), so Ca/P = 10/6 ≈ 1.67. Bone apatite contains carbonate ions and other species, and its Ca/P is somewhat lower than this. 1.50 is the ratio 3/2 of tricalcium phosphate (TCP, Ca₃(PO₄)₂). β-TCP is more soluble than hydroxyapatite and is used as a bioresorbable material that is resorbed in the body and replaced by bone. 1.33 is the ratio 8/6 of octacalcium phosphate (Ca₈H₂(PO₄)₆·5H₂O). If the Ca/P ratio of a synthesized powder deviates from 1.67, β-TCP or CaO forms as a by-product on firing, so controlling the composition is important.

Hydroxyapatite in the explanations

Questions that mention Hydroxyapatite (3)

  1. What is the Ca/P molar ratio of hydroxyapatite, Ca₁₀(PO₄)₆(OH)₂?
  2. Which of these is a bioactive ceramic that bonds directly and chemically to bone?
  3. Which statement correctly describes osseointegration, as the term is used for pure titanium in dental implants and similar devices?

Related terms

Osseointegration Passivity Bone cement Biocompatibility Biodegradable polymer Stress shielding Superelasticity β titanium alloy

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